Forging a Vision Together

The Center for Bioengineering is a community of researchers with common interests who contribute their varied expertise towards a shared mission of building a safer world. Put another way, the Center for Bioengineering is only as good as its people, and its successes are theirs.

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Our Team

The Center for Bioengineering’s affiliated staff collaboratively determine its research activities, foster collaboration with outside entities, and articulate the scope and vision for the center. Some affiliates are longstanding contributors, while others are aligned for shorter term projects. We introduce a few representative researchers below.

Elizabeth Wheeler

Elizabeth Wheeler

Director, Center for Bioengineering (acting)

Elizabeth Wheeler is currently serving as the Director of the Center for Bioengineering. She is also a staff scientist working in S Program and a group leader in the Materials Engineering Division.

She began her career at LLNL as a post-doctoral researcher working on NIF optics prior to joining the Center for Micro and Nano Technology. She has been involved with bioinstrumentation at LLNL for 14 years.

The majority of her career has focused on integrating biology and engineering to yield new platforms or flexible devices for Homeland Security or medical applications. She has worked on numerous multidisciplinary teams that have field tested technology developed at LLNL. Currently she is a team member on a Bioprinting Vasculature project and the Principal Investigator for a DNA Tagged Reagents for Aerosol Experiments (DNATrax) project.

In 2013, she won an R&D 100 award for her contributions to DNATrax. Her primary focus is currently the LDRD SI in-situ Chip-based Human Investigational Platform (iCHIP) project.

Elizabeth earned a B.S. in chemical engineering from the University of California, Davis and M.S. and PhD degrees in chemical engineering from Stanford University.

Allison Yorita

Allison Yorita

Staff Engineer, Implantables Microsystems Group

Allison Yorita joined LLNL in 2016 as a postdoctoral researcher, transitioning to staff engineer in 2019. Since then, she has led multiple projects as a principal investigator at LLNL, focused on flexible implantable arrays for detection of electrical and chemical signals in the body.

With a background in chemical engineering, her research focus has been in creating novel chemical sensors for detection of a variety of biomolecules and chemicals at high spatial and temporal resolution. Leveraging LLNL’s work in fabricating high channel count, flexible microelectrode arrays, she aims to add additional sensing modalities to the array platform for better insight into the body’s microenvironment, with a focus on the central and peripheral nervous system.

Allison comes to LLNL from the University of California, Los Angeles, where she obtained her Ph.D. in chemical engineering. Her graduate work focused on microfabrication and development of silicon-based chemical sensors for detection of neurotransmitters, as well as development of a bioelectronic diagnostic tool for sensitive, selective detection of nucleic acid sequences from pathogens.

Razi Haque

Razi Haque

Research Engineer & Group Leader, Implantable Microsystems Group

Razi Haque is a Research Engineer and the Implantable Microsystems Group Leader at Lawrence Livermore National Laboratory where he serves as principal investigator for a number of externally-funded research programs from the NIH and DARPA as well as internally-funded Laboratory Directed Research Development programs. The Implantable Microsystems Group primarily focuses on building flexible devices using microfabrication techniques and tools and leverages a quality management system to build human-grade implantable devices. The Group’s research focus is on next-generation neural interfaces and integrating multi-modal capabilities, including chemical and optical interfaces. Previously, Razi worked at a startup in southern California focusing on translating his graduate studies at the University of Michigan which focused on an intraocular implantable microsystem.

Daniel Faissol

Daniel Faissol

Program Lead, Predictive Design of Biologics

Dan Faissol is the program lead for predictive design of biologics at LLNL and leads LLNL’s initiative in deep reinforcement learning for national security applications. He currently serves on the LLNL Data Science Institute Council and as the lead for the computational and data science area within the LLNL Bioengineering Center.

Dan joined LLNL as postdoc in 2008 and served as group leader of the Operations Research and System Analysis group from 2013 to 2017. His current primary area of focus is in developing novel approaches for integrating artificial intelligence, simulation and experimental evaluations to accelerate design and scientific discovery, primarily applied to antibody and vaccine antigen design.

Dan earned his Ph.D. in Industrial and Systems Engineering at Georgia Institute of Technology, his M.S. in Economics from Georgia Institute of Technology, and his B.S. in Electrical Engineering at University of California, Los Angeles.

Doris Lam

Doris Lam (PLS)

Doris Lam is a neuroscientist specializing in neuroimmunology. Her research interest is in understanding the interaction between different cell types in the central nervous system (CNS). Her research has used multi-disciplinary approaches (electrophysiology, and cell and molecular biology) to identify mechanisms that regulate cellular activity in CNS cells (e.g. neurons and microglia), and how they contribute to neurodegenerative diseases. Lam's current work focuses on reproducing the CNS on an in-vitro, chip-based Human Investigational Platform.

Matt Coleman

Matt Coleman (PLS)

Matt is a senior staff biomedical scientist at Lawrence Livermore National Laboratory in the division of Biology and Biotechnology and an adjunct professor in the department of Radiation Oncology at the University of California at Davis. He has authored over 120 publications in peer-reviewed journals, published proceedings and book chapters covering a diverse breadth of molecular biology and biochemistry. Matt's major areas of research focus are in the area of radiobiology in support of cancer treatment and biodosimetry. His group has also been very active in the development of biotechnology and advance biochemical techniques around the areas of cell-free expression, membrane proteins and nanoparticles made of apolipoproteins called nanolipoprotein particles (NLPs).

Nick Fischer

Nick Fischer (PLS)

Nick Fischer has been a staff scientist in the Physical and Life Sciences (PLS) Directorate at Lawrence Livermore National Laboratory since 2008. He also worked as a Postdoctoral Fellow in PLS at LLNL under PI Jeffrey Tok. Prior to his tenure at LLNL, Fischer was a Research Assistant at the University of Massachusetts, Amherst where he completed his PhD in Molecular and Cellular Biology Program (2005). Fischer earned a B.S. in Biology at West Chester University of Pennsylvania.

Nick’s research Interests include biomimetic nanoparticle design for vaccine-related in vivo applications, in vitro tissue mimetic platforms, biomimetic nanoparticle development and characterization, molecular recognition elements and detection platforms, and metal-core nanoparticles and applications.

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